Multi-Class UHPLC-MS/MS Method for Plant Toxins and Cyanotoxins in Food Supplements and Application for Belgian Market Samples (#)

E Van Pamel, J Henrottin, C Van Poucke, N Gillard, E Daeseleire

Research output: Contribution to journalArticlepeer-review

Abstract

The presence of plant toxins and/or cyanotoxins in food supplements implies consumer health risks. Therefore, a targeted ultra-high performance liquid chromatographic-tandem mass spectrometric method to detect/quantify 25 toxins simultaneously in food supplement formulations was developed and validated. Full validation for tablets/powders and secondary validation for a liquid and soft gel capsule indicated that most compounds were efficiently extracted (>= 75%), while others were only partly extracted (18-61%). Trueness was fulfilled (70-120%), with some exceptions (mostly at the lowest validation level). Intralaboratory repeatability, intra- and interlaboratory reproducibility values of
Original languageEnglish
JournalPLANTA MEDICA
Volume87
Issue number12/13
Pages (from-to)1069-1079
Number of pages11
ISSN0032-0943
DOIs
Publication statusPublished - Jun-2021

Keywords

  • alkaloids
  • microcystin LR
  • thujone
  • Artemisia
  • Asteraceae
  • Borago
  • Boraginaceae
  • Aphanizomenon flos-aquae
  • Aphanizomenonaceae
  • TANDEM MASS-SPECTROMETRY
  • PYRROLIZIDINE ALKALOIDS
  • DIETARY-SUPPLEMENTS
  • MYCOTOXINS
  • BOTANICALS
  • FEED
  • QUANTIFICATION
  • MICROCYSTINS
  • QUANTITATION
  • PESTICIDES

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