TY - JOUR
T1 - Recent advances in recognition elements of food and environmental biosensors
T2 - a review
AU - Van Dorst, Bieke
AU - Mehta, Jaytry
AU - Bekaert, Karen
AU - Rouah-Martin, Elsa
AU - De Coen, Wim
AU - Dubruel, Peter
AU - Blust, Ronny
AU - Robbens, Johan
N1 - Copyright © 2010 Elsevier B.V. All rights reserved.
PY - 2010
Y1 - 2010
N2 - A sensitive monitoring of contaminants in food and environment, such as chemical compounds, toxins and pathogens, is essential to assess and avoid risks for both, human and environmental health. To accomplish this, there is a high need for sensitive, robust and cost-effective biosensors that make real time and in situ monitoring possible. Due to their high sensitivity, selectivity and versatility, affinity-based biosensors are interesting for monitoring contaminants in food and environment. Antibodies have long been the most popular affinity-based recognition elements, however recently a lot of research effort has been dedicated to the development of novel recognition elements with improved characteristics, like specificity, stability and cost-efficiency. This review discusses three of these innovative affinity-based recognition elements, namely, phages, nucleic acids and molecular imprinted polymers and gives an overview of biosensors for food and environmental applications where these novel affinity-based recognition elements are applied.
AB - A sensitive monitoring of contaminants in food and environment, such as chemical compounds, toxins and pathogens, is essential to assess and avoid risks for both, human and environmental health. To accomplish this, there is a high need for sensitive, robust and cost-effective biosensors that make real time and in situ monitoring possible. Due to their high sensitivity, selectivity and versatility, affinity-based biosensors are interesting for monitoring contaminants in food and environment. Antibodies have long been the most popular affinity-based recognition elements, however recently a lot of research effort has been dedicated to the development of novel recognition elements with improved characteristics, like specificity, stability and cost-efficiency. This review discusses three of these innovative affinity-based recognition elements, namely, phages, nucleic acids and molecular imprinted polymers and gives an overview of biosensors for food and environmental applications where these novel affinity-based recognition elements are applied.
KW - Bacteriophages
KW - Biosensing Techniques
KW - Environmental Health
KW - Environmental Pollutants
KW - Food Contamination
KW - Humans
KW - Molecular Imprinting
KW - Nucleic Acids
KW - Peptide Library
KW - Transducers
U2 - 10.1016/j.bios.2010.07.033
DO - 10.1016/j.bios.2010.07.033
M3 - A1: Web of Science-article
C2 - 20729060
SN - 0956-5663
VL - 26
SP - 1178
EP - 1194
JO - Biosensors & Bioelectronics
JF - Biosensors & Bioelectronics
IS - 4
ER -