Updated safety evaluation of the food enzyme isoamylase from the Dyella sp. strain MU 1174


Research output: Contribution to journalA1: Web of Science-articlepeer-review


The food enzyme isoamylase (glycogen α-1,6-glucanohydrolase, EC is produced with Dyella sp. strain MU 1174 by Hayashibara Co. Ltd. In a previous opinion, the Panel on Food Contact Materials, Enzymes and Processing Aids of EFSA could not conclude on the safety of this food enzyme due to uncertainties about the presence of a gene conferring resistance to antimicrobials in the genome of the production strain and its potential transfer to the food enzyme. New whole genome sequence data provided by the applicant showed that the production strain Dyella sp. MU 1174 does not contain antimicrobial resistance genes of concern. Based on the new data provided and the evaluation of the data previously submitted, the Panel concludes that this food enzyme does not give rise to safety concerns under the intended conditions of use.
Original languageEnglish
JournalEFSA Journal
Issue number10
Pages (from-to)e06871
Number of pages7
Publication statusPublished - 1-Oct-2021

Cite this