Validation of the βeta-s.t.a.r. Combo for fast screening of raw milk on the presence of ß-lactam antibiotics and tetracyclines

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    Abstract

    The 5-minute test ßeta-s.t.a.r. Combo (Neogen Corporation, Lansing, MI) was validated at ILVO-T&V according to Commission Decision 2002/657/EC and the CRL Guidelines for the validation of screening methods by determination of the test specificity, detection capabilities and test robustness.
    In the validation study the test showed to be very specific as a real interference was only caused by clavulanic acid at 700 µg/kg and above. The ßeta-s.t.a.r. Combo detects all ß-lactams and tetracyclines with a MRL in milk at their respective MRL except for cefalexin and desfuroylceftiofur.
    Positive results for milk with an abnormal composition/quality should be considered with caution since interferences (false positive results) were observed. Retesting of initially positive milk samples could be a recommendation.
    Original languageEnglish
    Title of host publicationResidues of veterinary drugs in food : Proceedings of the EuroResidue VII Conference, Egmond aan Zee, The Netherlands, 14-16 May 2012
    EditorsRobert Schilt
    Number of pages6
    Volume2
    Publication date2012
    Pages557-562
    ISBN (Print)978-94-6173-318-4
    Publication statusPublished - 2012
    EventEuroResidue VII Conference on Residues of Veterinary Drugs in Food - Egmond aan Zee, Egmond aan Zee, Netherlands
    Duration: 14-May-201216-May-2012

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