In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components

Lien Vande Maele; Marc Heyndrickx; Dominiek Maes; Nele DE Pauw; Maxime Mahu; Marc Verlinden; Freddy Haesebrouck; An Martel; Frank Pasmans; Filip Boyen

doi:10.1292/jvms.15-0341

In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components

Lien Vande Maele, Marc Heyndrickx, Dominiek Maes, Nele DE Pauw, Maxime Mahu, Marc Verlinden, Freddy Haesebrouck, An Martel, Frank Pasmans, Filip Boyen

Onderzoeksoutput: Bijdrage aan tijdschrift › A1: Web of Science-artikel › peer review

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The antibacterial potential of organic acids and essential oil components against Brachyspira hyodysenteriae, the causative pathogen of swine dysentery, was evaluated. Minimum inhibitory concentrations (MIC) of 15 compounds were determined at pH 7.2 and pH 6.0, using a broth microdilution assay. In addition, possible synergism was determined. MIC values for the three tested strains were similar. For organic acids, MIC values at pH 6.0 were lower than at pH 7.2. B. hyodysenteriae was most sensitive to cinnamaldehyde and lauric acid, with MIC values <1.5 mM. Most antibacterial effects of binary combinations were additive, however, for thymol and carvacrol, synergism could be observed. In vitro results demonstrate the antibacterial action of certain essential oil components and organic acids against B. hyodysenteriae.

Oorspronkelijke taal	Engels
Tijdschrift	The Journal of veterinary medical science / the Japanese Society of Veterinary Science
Volume	78
Exemplaarnummer	2
Pagina's (van-tot)	325-328
DOI's	https://doi.org/10.1292/jvms.15-0341
Publicatiestatus	Gepubliceerd - 2016

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10.1292/jvms.15-0341

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Vande Maele, L., Heyndrickx, M., Maes, D., DE Pauw, N., Mahu, M., Verlinden, M., Haesebrouck, F., Martel, A., Pasmans, F., & Boyen, F. (2016). In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components. The Journal of veterinary medical science / the Japanese Society of Veterinary Science, 78(2), 325-328. https://doi.org/10.1292/jvms.15-0341

@article{c42f612e056b4e0cbdcab2fe4cac3a6d,

title = "In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components",

abstract = "The antibacterial potential of organic acids and essential oil components against Brachyspira hyodysenteriae, the causative pathogen of swine dysentery, was evaluated. Minimum inhibitory concentrations (MIC) of 15 compounds were determined at pH 7.2 and pH 6.0, using a broth microdilution assay. In addition, possible synergism was determined. MIC values for the three tested strains were similar. For organic acids, MIC values at pH 6.0 were lower than at pH 7.2. B. hyodysenteriae was most sensitive to cinnamaldehyde and lauric acid, with MIC values <1.5 mM. Most antibacterial effects of binary combinations were additive, however, for thymol and carvacrol, synergism could be observed. In vitro results demonstrate the antibacterial action of certain essential oil components and organic acids against B. hyodysenteriae.",

author = "{Vande Maele}, Lien and Marc Heyndrickx and Dominiek Maes and {DE Pauw}, Nele and Maxime Mahu and Marc Verlinden and Freddy Haesebrouck and An Martel and Frank Pasmans and Filip Boyen",

year = "2016",

doi = "10.1292/jvms.15-0341",

language = "English",

volume = "78",

pages = "325--328",

journal = "The Journal of veterinary medical science / the Japanese Society of Veterinary Science",

issn = "1347-7439",

publisher = "Japanese Society of Veterinary Science",

number = "2",

}

Vande Maele, L, Heyndrickx, M, Maes, D, DE Pauw, N, Mahu, M, Verlinden, M, Haesebrouck, F, Martel, A, Pasmans, F & Boyen, F 2016, 'In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components', The Journal of veterinary medical science / the Japanese Society of Veterinary Science, vol. 78, nr. 2, blz. 325-328. https://doi.org/10.1292/jvms.15-0341

In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components. / Vande Maele, Lien; Heyndrickx, Marc; Maes, Dominiek et al.
In: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, Vol. 78, Nr. 2, 2016, blz. 325-328.

Onderzoeksoutput: Bijdrage aan tijdschrift › A1: Web of Science-artikel › peer review

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T1 - In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components

AU - Vande Maele, Lien

AU - Heyndrickx, Marc

AU - Maes, Dominiek

AU - DE Pauw, Nele

AU - Mahu, Maxime

AU - Verlinden, Marc

AU - Haesebrouck, Freddy

AU - Martel, An

AU - Pasmans, Frank

AU - Boyen, Filip

PY - 2016

Y1 - 2016

N2 - The antibacterial potential of organic acids and essential oil components against Brachyspira hyodysenteriae, the causative pathogen of swine dysentery, was evaluated. Minimum inhibitory concentrations (MIC) of 15 compounds were determined at pH 7.2 and pH 6.0, using a broth microdilution assay. In addition, possible synergism was determined. MIC values for the three tested strains were similar. For organic acids, MIC values at pH 6.0 were lower than at pH 7.2. B. hyodysenteriae was most sensitive to cinnamaldehyde and lauric acid, with MIC values <1.5 mM. Most antibacterial effects of binary combinations were additive, however, for thymol and carvacrol, synergism could be observed. In vitro results demonstrate the antibacterial action of certain essential oil components and organic acids against B. hyodysenteriae.

AB - The antibacterial potential of organic acids and essential oil components against Brachyspira hyodysenteriae, the causative pathogen of swine dysentery, was evaluated. Minimum inhibitory concentrations (MIC) of 15 compounds were determined at pH 7.2 and pH 6.0, using a broth microdilution assay. In addition, possible synergism was determined. MIC values for the three tested strains were similar. For organic acids, MIC values at pH 6.0 were lower than at pH 7.2. B. hyodysenteriae was most sensitive to cinnamaldehyde and lauric acid, with MIC values <1.5 mM. Most antibacterial effects of binary combinations were additive, however, for thymol and carvacrol, synergism could be observed. In vitro results demonstrate the antibacterial action of certain essential oil components and organic acids against B. hyodysenteriae.

U2 - 10.1292/jvms.15-0341

DO - 10.1292/jvms.15-0341

M3 - A1: Web of Science-article

C2 - 26369432

SN - 1347-7439

VL - 78

SP - 325

EP - 328

JO - The Journal of veterinary medical science / the Japanese Society of Veterinary Science

JF - The Journal of veterinary medical science / the Japanese Society of Veterinary Science

IS - 2

ER -

In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components

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