Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 10: Quinolones: flumequine and oxolinic acid

EFSA BIOHAZ Panel

Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikelpeer review

Uittreksel

The specific concentrations of flumequine and oxolinic acid in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health, as well as the specific antimicrobial concentrations in feed which have an effect in terms of growth promotion/increased yield were assessed by EFSA in collaboration with EMA. Details of the methodology used for this assessment, associated data gaps and uncertainties, are presented in a separate document. To address antimicrobial resistance, the Feed Antimicrobial Resistance Selection Concentration (FARSC) model developed specifically for the assessment was applied. However, due to the lack of data on the parameters required to calculate the FARSC, it was not possible to conclude the assessment until further experimental data are available. To address growth promotion, data from scientific publications obtained from an extensive literature review were used. No suitable data for the assessment were available. It was recommended to carry out studies to generate the data that are required to fill the gaps which prevented the calculation of the FARSC for these antimicrobials.
Oorspronkelijke taalEngels
TijdschriftEFSA Journal
Volume19
Exemplaarnummer10
Pagina's (van-tot)e06862
Aantal pagina’s18
ISSN1831-4732
DOI's
PublicatiestatusGepubliceerd - 1-okt-2021

Trefwoorden

  • antimicrobial resistance
  • flumequine
  • food-producing animals
  • growth promotion
  • oxolinic acid
  • sub-inhibitory concentration
  • yield increase

Dit citeren