Robust and validated analytical methods are needed for the implementation of GM-food and feed legislation. The validation, based on the characterisation of a method for its sensitivity, accuracy and precision, is performed in-house or in collaborative trials according to good laboratory practice to comply with internationally harmonised standards. The way in which this is implemented depends on the analyte, influences of the food/feed matrix and other requirements that need to be met. Certified reference materials, when matrix matches and contains the appropriate concentration of the certified analyte, are a useful tool in validation. Some acceptability criteria, associated to ad-hoc statistics (e.g. percent bias, repeatability and reproducibility) are useful for the purposes of testing and decision-making. However, the interpretation of validation results also depends on professional judgment and expertise. In such respect, fuzzy logic-based techniques (complementary to conventional statistics) are advocated to support the continuous progress of GMO science and routine laboratory analyses.
|Genetically modified and non-genetically modified food supply chains : co-existence and traceability
|ISBN van geprinte versie
|Gepubliceerd - nov.-2012