Safety and efficacy of a feed additive consisting on Ligilactobacillus animalis ATCC PTA-6750 (formerly Lactobacillus animalis) for all animal species (Chr. Hansen A/S)

EFSA FEEDAP Panel, Lieve Herman

Onderzoeksoutput: Bijdrage aan tijdschriftA1: Web of Science-artikelpeer review


Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the additive consisting of Ligilactobacillus animalis (formerly known as Lactobacillus animalis) ATCC PTA-6750 when used as a technological additive (acidity regulator, preservative and hygiene condition enhancer) in feed and water for drinking for all animal species. The product is intended for use as a single strain at a minimum inclusion level of 5 × 106 CFU/L or CFU/kg in water, liquid and dry feeds. No minimum inclusion level is proposed by the applicant when used in combination with other microbial technological additives. The bacterial species L. animalis is considered by EFSA to be eligible for the qualified presumption of safety approach. As the identity of the strain has been clearly established and it did not show acquired resistance to antibiotics of human and veterinary importance, the use of the strain in animal nutrition is considered safe for the target species, consumers and the environment. No conclusions can be drawn on the skin/eye irritancy or skin sensitisation potential of the product, but it should be considered a respiratory sensitiser. Exposure of users by inhalation is likely. The Panel is not in the position to conclude on the efficacy of L. animalis ATCC PTA-6750 when used in animal nutrition as an acidity regulator, preservative or hygiene condition enhancer due to lack of data. The studies provided showed that L. animalis ATCC PTA-6750 when used in combination with Propionibacterium freudenreichii ssp. shermanii ATCC PTA-6752 has the potential to act as an acidity regulator. However, the Panel has reservations on the effects of this mixture in practical use conditions.
Oorspronkelijke taalEngels
Artikel nummer6469
TijdschriftEFSA Journal
Pagina's (van-tot)e06469
Aantal pagina’s11
PublicatiestatusGepubliceerd - 1-mrt-2021


  • Ligilactobacillus animalis ATCC PTA-6750
  • acidity regulator
  • efficacy
  • hygiene condition enhancer
  • preservative
  • safety
  • technological additive

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